Knoxville, Texas was an early settlement founded by the Norman family from Knoxville, Tennessee. I think it was Sam Norman (and father of Thomas Norman) that founded this town. According to TSHA (Texas State Historical Association) Knoxville, Texas was founded by immigrants from Tennessee in the late 1840s. In 1854 Thomas Norman sold 2/3 interest of the land to William Pope and Archibald Carmichael. Later in 1854 a post office opened and Knoxville became a town in Cherokee County, Texas. Also in 1854 William Pope opened a general store. During the US Civil War Knoxville had four general stores, a gristmill, sawmill, distillery (for whiskey sold in general stores), tanyard, and a church that served several denominations. In the early 1870s the railroad bypassed Knoxville; and in 1875 the post office closed.